A common feature of chronic kidney disease especially in maintain hemodialysis patients is the mineral metabolism. Among other biochemical parameters known for vascular calcification and cardiovascular morbidity are the calcium phosphate concentrations (Ca×P). To test whether renal function biomarkers associated on hemodialysis patients are related to the mineral metabolism we undertook an observational, cross-sectional study on 110 maintenance hemodialysis patients in the clinic with their data and medical history. Our patients’ demography and laboratory parameters (hemoglobin, ferritin, glucose, urea, creatinine, calcium, phosphate and albumin) were obtainable from the patients’ medical records. The Ca×P product was determined using the concentration of serum calcium and phosphate. Statistical analysis was conducted using descriptive statistics and correlation analysis. Mean Ca×P product was 42.31 ± 12.44 mg²/dL² and significant positive relation between Ca×P product and serum phosphate was found (r = 0.52 p < 0.001) while the same correlation happened for serum creatinine (r = 0.45 p < 0.001). No correlation was noted with Ca×P product and albumin. The phosphate retention and renal dysfunction are the factors of mineral metabolism deterioration seen in hemodialysis patients. Therefore, monitoring Ca×P product would be an important therapeutic and clinical marker for determining if there is a mineral derangement of dialysis patients to guide treatment