This review examines the critical role of psychological factors in a patient’s adaptation to complete dentures. It synthesizes evidence showing that a patient’s expectations, personality type, past experiences, and cognitive state significantly influence the adaptation period. Furthermore, the dentist-patient relationship and the often-overlooked influence of a patient’s social circle are discussed as key determinants of success. The paper concludes that a holistic approach, combining clinical skill with psychological support and patient education, is essential for reducing adaptation time and improving overall treatment outcomes for edentulous patients.